Researching different approaches to administration
Different types of administration are being researched.
Garrett has severe
hemophilia A.
Researching different approaches to administration
Different types of administration are being researched.
Investigational administration
Patients express concerns and burdens associated with administration. Different approaches to administration of hemophilia therapy are being researched.1-4
Dosing frequency and adherence
According to some patients, dosing frequency is an important part of their treatment choice and their ability to adhere to a dosing regimen. Scientists are researching ways to address these concerns.1,4-7
Patients have expressed a desire for fewer infusions to reduce their treatment burden. Some patients believe that having a regular routine for prophylaxis could help them with adherence and remembering therapy.8
Exploration doesn’t stop with administration
Scientists are also researching different approaches to coagulation: hemostasis via anticoagulant inhibition rather than procoagulant addition.
Garrett has severe hemophilia A.
Garrett has severe hemophilia A.
Stay in the know
Keep up with research in hemophilia.
References:
- Wiley RE, Khoury CP, Snihur AWK, et al. From the voices of people with haemophilia A and their caregivers: challenges with current treatment, their impact on quality of life and desired improvements in future therapies. Haemophilia. 2019;25(3):433-440.
- Srivastava A, Santagostino E, Dougall A, et al. WFH Guidelines for the Management of Hemophilia, 3rd edition [published correction appears in Haemophilia. 2021 Jul;27(4):699]. Haemophilia. 2020;26(suppl 6):1-158.
- Fifer S, Kerr AM, Parken C, Hamrosi K, Eid S. Treatment preferences in people with haemophilia A or caregivers of people with haemophilia A: a discrete choice experiment. Haemophilia. 2020;26(suppl 5):30-40.
- Park YS, Hwang TJ, Cho GJ, et al. Patients' and parents' satisfaction with, and preference for, haemophilia A treatments: a cross-sectional, multicentre, observational study. Haemophilia. 2021;27(4):563-573.
- Sun SX, Zhao J, Yang H, Wu E. Patient preferences for hemophilia A treatments: a discrete choice experiment. Blood. 2020;136(suppl 1):22.
- Joshi N, Ng X, Botteman M, et al. Patients’ and caregivers’ preferences for different hemophilia A treatment attributes. Blood. 2019;134(suppl 1):2122.
- Benton M, Patel AM, Shi L, et al. Assessing patient and caregiver preferences for treatment of haemophilia A: a discrete choice experiment. Haemophilia. 2021;27(4):e479-e483.
- Khair K, Gibson F, Meerabeau L. The benefits of prophylaxis: views of adolescents with severe haemophilia. Haemophilia. 2012;18(3):e286-e289.
